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Article

Glc7/PP1 triggers Paf1 complex dissociation from RNA polymerase II to enable transcription termination.

Genes & development - 4 May 2026

Namjilsuren Sanchirmaa, Arndt Karen M

Abstract excerpt

The mechanisms that control the dynamic composition of RNAPII elongation complexes govern major transitions in the transcription cycle yet are poorly understood. Here, we show that the transcription elongation factor Spt5 determines elongation complex composition to promote productive elongation and the transition to termination. Using an unbiased genetic screen and genomic approaches in Saccharomyces cerevisiae,...

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Share to Chromosomal Proteins, Non-Histone
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41791865
DOI: 10.1101/gad.353379.125
PMCID: PMC13078362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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