Article

Ssl2/TFIIH function in Transcription Start Site Scanning by RNA Polymerase II in <i>Saccharomyces cerevisiae</i>

2021-05-05

Abstract excerpt

<h4>ABSTRACT</h4> In Saccharomyces cerevisiae , RNA Polymerase II (Pol II) selects transcription start sites (TSS) by a unidirectional scanning process. During scanning, a preinitiation complex (PIC) assembled at an upstream core promoter initiates at select positions within a window ∼40-120 basepairs downstream. Several lines of evidence indicate that Ssl2, the yeast homolog of XPB and an essential and conserve...

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Literature Corpus work: d6d0ece0-6219-5865-a690-e1c73ffe8492
DOI: 10.1101/2021.05.05.442816

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