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Article

Dynamic Gene Expression Signatures across Stages of Carotid Plaque Calcification.

Journal of vascular research - 1 Jan 2026

Katano Hiroyuki, Yamanaka Tomoyasu, Shibata Teishiki, Inoue Yasuhide, Nishikawa Yusuke, Yamada Shigeki, Tanikawa Motoki, Yamada Kazuo, Mase Mitsuhito

Abstract excerpt

<p>Introduction: The aims of the study were to elucidate gene expression changes associated with different stages of calcification in carotid artery plaques and clarify the dynamic biological processes underlying plaque maturation. METHODS: Carotid plaque specimens were classified into four groups - mildly, moderately, severely, and very severely calcified - based on calcium scores derived from computed...

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Share to Carotid Arteries
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Muscle, Smooth, Vascular

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Share to Plaque, Atherosclerotic

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Source

Open in PubMed Open full text

Identifiers

PMID: 41553961
DOI: 10.1159/000550336
PMCID: PMC12959890

Genes

ACTA2
CD68
ELN
MYH11
RUNX2
SPP1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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