Article

Atherosclerotic fibrous plaques in females are characterized by endothelial-to-mesenchymal transition and linked to smoking

2024-10-02

Abstract excerpt

<h4>Background</h4> Sex and plaque histology are intertwined, with fibrous atherosclerotic plaques being more prevalent in women and pointing to general smooth muscle cell plasticity and estrogen signaling. Plaque erosion, a significant contributor to acute coronary syndromes (ACSs), is linked to fibrous plaques and is more prevalent in women as compared to men. We hypothesize that the molecular drivers of histolo...

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Literature Corpus work: 0b77a93d-2560-579e-b321-b190d1fba48d
DOI: 10.1101/2024.10.01.24314739

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