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Article

Plaque Calcification During Atherosclerosis Progression and Regression.

Journal of atherosclerosis and thrombosis - 1 Apr 2018

Shioi Atsushi, Ikari Yuji

Abstract excerpt

Plaque calcification develops by the inflammation-dependent mechanisms involved in progression and regression of atherosclerosis. Macrophages can undergo two distinct polarization states, that is, pro-inflammatory M1 phenotype in progression and anti-inflammatory M2 phenotype in regression. In plaque progression, predominant M1 macrophages promote the initial calcium deposition within the necrotic core of the...

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Identifiers

PMID: 29238011
DOI: 10.5551/jat.RV17020
PMCID: PMC5906181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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