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Article

A Mendelian randomization study investigating the causal relationships between inflammation and immunoglobulin A nephropathy.

Human immunology - 1 Jul 2024

Ren Yi, Zhang Honggang

Abstract excerpt

BACKGROUND: Immunoglobulin A nephropathy (IgAN) is an autoimmune disease characterized by the production of galactose‑deficient IgA1 (Gd‑IgA1) and the deposition of immune complexes in the kidney. Exploring the landscape of immune dysregulation in IgAN is valuable for pathogenesis and disease treatment. We conducted Mendelian randomization (MR) to assess the causal correlations between inflammation and IgAN....

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Source

Identifiers

PMID: 38861759
DOI: 10.1016/j.humimm.2024.110830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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