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Immunoglobulin G N-glycan, inflammation and type 2 diabetes in East Asian and European populations: a Mendelian randomization study

14 Sept 2022

Abstract excerpt

BACKGROUND: Immunoglobulin G (IgG) N-glycans have been shown to be associated with the risk of type 2 diabetes (T2D) and its risk factors. However, whether these associations reflect causal effects remain unclear. Furthermore, the associations of IgG N-glycans and inflammation are not fully understood. METHODS: We examined the causal associations of IgG N-glycans with inflammation (C-reactive protein (CRP) and...

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PMID: 36104772
DOI: 10.1186/s10020-022-00543-z

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