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Article

Environmental, Psychiatric, and Genetic Predictors of Alcohol Use Disorder Criterion Count: Analyses of African and European Ancestries.

The American journal of psychiatry - 1 Nov 2025

Na Peter J, Deak Joseph D, Levey Daniel F, Kember Rachel L, Kranzler Henry R, Pietrzak Robert H, Gelernter Joel

Abstract excerpt

OBJECTIVE: Quantifying the contribution of environmental and genetic factors to alcohol use disorder (AUD) criterion count across different ancestries may provide insight into the biopsychosocial etiology of AUD. Although polygenic risk prediction represents an important future application, its utility may be enhanced when considered in the context of environmental predictors. The authors used large African- and...

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Identifiers

PMID: 40988466
DOI: 10.1176/appi.ajp.20240893
PMCID: PMC13059437

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