Article

Predicting Treatment-seeking Status for Alcohol Use Disorder Using Polygenic Scores and Machine Learning in a Deeply-Phenotyped Sample

2024-11-23

Abstract excerpt

<h4>Background</h4> Few individuals with alcohol use disorder (AUD) receive treatment. Previous studies have shown drinking behavior, psychological problems, and substance dependence to predict treatment seeking. However, to date, no studies have incorporated polygenic scores (PGS), a measure of genetic risk for AUD. <h4>Methods</h4> Using the Yale-Penn sample, we identified 9,103 individuals diagnosed with DSM-IV...

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Literature Corpus work: cd2c848e-9a09-55d9-9b9d-862e1ad149f9
DOI: 10.1101/2024.11.22.24317810

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