Article

Clinical, Environmental, and Genetic Risk Factors for Substance Use Disorders: Characterizing Combined Effects across Multiple Cohorts

2022-01-28

Abstract excerpt

<h4>ABSTRACT</h4> Substance use disorders (SUDs) incur serious social and personal costs. Risk for SUDs is complex, ranging from social conditions to individual genetic variation. We examined whether models that include a clinical/environmental risk index (CERI) and polygenic scores (PGS) are able to identify individuals at increased risk of SUD in young adulthood across four longitudinal cohorts for a combined sa...

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Literature Corpus work: 4c00384a-1279-562e-af66-f34d38ac1976
DOI: 10.1101/2022.01.27.22269750

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