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Article

KRAS oncogenic mutations in benign tumors: adenomatoid odontogenic tumor as a model.

Mutation research. Reviews in mutation research - 1 Jan 2025

Coura Bruna Pizziolo, Guimarães Letícia Martins, Gomez Ricardo Santiago, Gomes Carolina Cavaliéri

Abstract excerpt

The KRAS protein is a GTPase that plays a role in the MAPK/ERK signaling pathway and KRAS is one of the most frequently mutated proto-oncogenes in malignant neoplasms, including aggressive tumors such as lung, pancreatic, and colorectal cancer. Mutations in KRAS, previously considered oncogenic drivers and hallmarks of cancer, have been observed at a high frequency in benign sporadic tumors, including those with...

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Identifiers

PMID: 40619091
DOI: 10.1016/j.mrrev.2025.108552

Genes

KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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KRAS oncogenic mutations in benign tumors: adenomatoid odontogenic tumor as a model.PMID 40619091Read ↗

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