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Article

Alterations of TGFBR2 and KRAS in cemento-osseous dysplasia of the jaw.

Oral surgery, oral medicine, oral pathology and oral radiology - 1 Oct 2025

Owosho Adepitan A, Shahrabi-Farahani Shokoufeh, Okhuaihesuyi Osariemen, Holt Jeremiah, Zhao Xiaobei, Hayes D Neil

Abstract excerpt

OBJECTIVE: Cemento-osseous dysplasia (COD) is a common benign fibro-osseous lesion found in the periapical regions of the jaw. Despite its prevalence, the etiopathogenesis of COD remains largely unknown. We conducted targeted sequencing of 1,036 genes on two nondecalcified formalin-fixed, paraffin-embedded COD tissue samples. STUDY DESIGN: The Promega Maxwell system was used for DNA isolation, while the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40527713
DOI: 10.1016/j.oooo.2025.05.008

Genes

TGFBR2
KRAS

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