Article
KRAS gene mutations in lung cancer: particulars established and issues unresolved.
Pathology international - 1 Oct 2010
Okudela Koji, Woo Tetsukan, Kitamura Hitoshi
Abstract excerpt
Lung cancer, like other cancers, is considered to develop through the accumulation of genetic alterations. Mutation of the KRAS gene is one of the most important events in carcinogenesis of the lung. The KRAS gene, belonging to the RAS gene family, encodes a membrane-bound 21-kd guanosine triphos...
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