Article
Malfeasance of KRAS mutations in carcinogenesis.
Clinical and experimental medicine - 1 Aug 2021
Tripathi Rupal, Nathany Shrinidhi, Mehta Anurag, Batra Ullas, Mattoo Sakshi, Sharma Mansi
Abstract excerpt
Activating mutations in the KRAS gene (Kirsten rat sarcoma 2 viral oncogene homolog gene) are commonly seen across the various solid organ and hematolymphoid neoplasms. With the likelihood of the mutation specific KRAS inhibitor entering clinical practice, the present studies profiled the landscape of these mutations in the Indian population to add to databases and posit the clinical utility of its emerging...
Topics
- Aged
- Carcinoma, Non-Small-Cell Lung
- Female
- Humans
- India
- Lung Neoplasms
- Male
- Middle Aged
- Mutation
- Proto-Oncogene Proteins p21(ras)