Article
The hidden costs of imperfection: transcription errors in protein aggregation diseases.
Current opinion in genetics & development - 1 Aug 2025
Sun Yingwo, Vermulst Marc
Abstract excerpt
At first glance, biological systems appear to operate with remarkable precision and order. Yet, closer examination reveals that this perfection is an illusion, biological processes are inherently prone to errors. Here, we describe recent evidence that indicates that errors that occur during transcription play an important role in neurological diseases. These errors, though transient, can have lasting consequences...
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