Article
Aberrant TERT expression: linking chronic inflammation to hepatocellular carcinoma†
11 Apr 2025
Abstract excerpt
Telomerase reverse transcriptase (TERT), the catalytic enzyme component of telomerase, plays multiple roles in cellular biology. Its canonical function is primarily associated with telomere maintenance and genomic stability. In addition, several studies revealed critical non-canonical extra-telomeric functions of TERT in various cellular processes, including cell proliferation and survival, DNA damage response,...
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