Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The regulations of telomerase reverse transcriptase (TERT) in cancer

26 Jan 2024

Abstract excerpt

Abnormal activation of telomerase occurs in most cancer types, which facilitates escaping from cell senescence. As the key component of telomerase, telomerase reverse transcriptase (TERT) is regulated by various regulation pathways. TERT gene changing in its promoter and phosphorylation respectively leads to TERT ectopic expression at the transcription and protein levels. The co-interacting factors play an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Research and Treatments
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38278800
DOI: 10.1038/s41419-024-06454-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The regulations of telomerase reverse transcriptase (TERT) in cancerPMID 38278800Read ↗

Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new playersSemantic proximity Read ↗

TERT—Regulation and Roles in Cancer FormationSemantic proximity Read ↗

Telomerase Reverse Transcriptase (TERT) in Action: Cross-Talking with EpigeneticsSemantic proximity Read ↗

Current Insights to Regulation and Role of Telomerase in Human DiseasesSemantic proximity Read ↗

Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancerSemantic proximity Read ↗

Noncanonical functions of telomerase and telomeres in viruses‐associated cancerSemantic proximity Read ↗

Mechanisms of TERT Reactivation and Its Interaction with BRAFV600E.Semantic proximity Read ↗

Reactivation of telomerase in cancer.Semantic proximity Read ↗

Telomeres and telomerase in oncogenesis (Review)Semantic proximity Read ↗

Telomerase Regulation: A Role for EpigeneticsSemantic proximity Read ↗

Telomerase Reverse Transcriptase (TERT) Regulation in Thyroid Cancer: A ReviewSemantic proximity Read ↗

The Molecular Interplay between Human Oncoviruses and Telomerase in Cancer DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.