Effect of ABCG2 c.421 C> A (rs2231142) single nucleotide polymorphisms on the lipid-modulating efficacy of rosuvastatin: a meta-analysis.

doi:10.1186/s12872-025-04611-0

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Article

Effect of ABCG2 c.421 C> A (rs2231142) single nucleotide polymorphisms on the lipid-modulating efficacy of rosuvastatin: a meta-analysis.

BMC cardiovascular disorders - 13 Mar 2025

Liu Lingyan, Deng Yongkun, Li Peng, Zhang Zhidan, Li Huiyou, Yang Xingbiao, Yin Zhaoheng, Lai Yong

Abstract excerpt

BACKGROUND: To systematically evaluate the effect of ABCG2 c.421 C > A (rs2231142) single nucleotide polymorphism (SNP) on the lipid-modulating efficacy of rosuvastatin (RST). METHODS: Searches were conducted using the Wan Fang database, Web of Science, Embase, PubMed, Cochrane Library, and China Journal Full Text Database. The time frame for the search was from the database's creation to September 1, 2024. The...

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PMID: 40082758
DOI: 10.1186/s12872-025-04611-0
PMCID: PMC11905716

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ABCG2
TG

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