Article
Meta-Analysis of the SLCO1B1 c.521T>C Variant Reveals Slight Influence on the Lipid-Lowering Efficacy of Statins.
Annals of laboratory medicine - 1 May 2015
Dou Ye, Zhu Xiaohai, Wang Qinglu, Tian Xuewen, Cheng Jingjing, Zhang Enying
Abstract excerpt
BACKGROUND: Several studies have focused on the association between the lipid-lowering efficacy of statins and the SLCO1B1 c.521T>C polymorphism; however, the results are conflicting. The effects of statins show significant variability between individuals. This meta-analysis aimed to investigate the effects of the SLCO1B1 c.521T>C polymorphism on the lipid-lowering effects of statins. METHODS: We systematically...
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