ABCG2 polymorphism is associated with the low-density lipoprotein cholesterol response to rosuvastatin.

doi:10.1038/clpt.2009.232

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Article

ABCG2 polymorphism is associated with the low-density lipoprotein cholesterol response to rosuvastatin.

Clinical pharmacology and therapeutics - 1 May 2010

Tomlinson B, Hu M, Lee V W Y, Lui S S H, Chu T T W, Poon E W M, Ko G T C, Baum L, Tam L S, Li E K

Abstract excerpt

The ATP-binding cassette G2 (ABCG2) c.421C>A (rs2231142) polymorphism influences the pharmacokinetics of rosuvastatin. We examined whether this polymorphism influences the low-density lipoprotein cholesterol (LDL-C)-lowering efficacy of the drug. In 305 Chinese patients with hypercholesterolemia...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2

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Identifiers

PMID: 20130569
DOI: 10.1038/clpt.2009.232

Genes

ABCG2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20130569-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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ABCG2 polymorphism is associated with the low-density lipoprotein cholesterol response to rosuvastatin.PMID 20130569Read ↗

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ABCB1 gene polymorphisms, ABCB1 haplotypes and ABCG2 c.421c > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics.Semantic proximity Read ↗

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