Article
Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.
Pharmacogenetics and genomics - 1 Oct 2010
Hu Miao, Lui Sandra S H, Mak Valiant W L, Chu Tanya T W, Lee Vivian W Y, Poon Emily W M, Tsui Teresa K C, Ko Gary T C, Baum Larry, Tam Lai-Shan, Li Edmund K, Tomlinson Brian
Abstract excerpt
Lipid changes with statin treatments vary greatly between individuals for reasons which are largely unknown. This study was performed to examine the genetic determinants of lipid responses to rosuvastatin in Chinese patients. A total of 125 polymorphisms in 61 candidate genes from 386 Chinese patients were analyzed for association with the lipid responses to rosuvastatin 10 mg daily. The polymorphisms most highly...
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