Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Monitoring the KMT2A gene post‐chemotherapy independently predicts the relapse and survival risk after allogeneic haematopoietic stem cell transplantation

13 Mar 2025

Abstract excerpt

This study evaluated the kinetics of KMT2A-r during chemotherapy and its impact on allogeneic haematopoietic stem cell transplantation (allo-HSCT) outcomes. KMT2A-r was assessed post-induction (MRD1), after the first (MRD2) and second (MRD3) consolidations and pre-transplant (MRD4) in 52 patients with acute myeloid leukaemia (AML). KMT2A-r significantly decreased from diagnosis to MRD2 (p < 0.001 for diagnosis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Acute Myeloid Leukemia Research
Share to Hematopoietic Stem Cell Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40081934
DOI: 10.1111/bjh.20036

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Monitoring the KMT2A gene post‐chemotherapy independently predicts the relapse and survival risk after allogeneic haematopoietic stem cell transplantationPMID 40081934Read ↗

Characteristics and Prognostic Implications in Newly Diagnosed KMT2Ar AML: A Multicenter Study of the ECLA Group.Semantic proximity Read ↗

Characteristics and outcomes of newly diagnosed acute myeloid Leukemia with KMT2A rearrangements.Semantic proximity Read ↗

Comprehensive immunophenotypic study of acute myeloid leukemia with KMT2A ( MLL ) rearrangement in adults: A single‐institution experienceSemantic proximity Read ↗

Updates in KMT2A Gene Rearrangement in Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Predictors of outcomes in adults with acute myeloid leukemia and KMT2A rearrangements.Semantic proximity Read ↗

The Landscape of KMT2A‐PTD AML: Concurrent Mutations, Gene Expression Signatures, and Clinical OutcomeSemantic proximity Read ↗

KMT2A Rearrangements in Leukemias: Molecular Aspects and Therapeutic PerspectivesSemantic proximity Read ↗

Hematopoietic stem cell transplantation for pediatric acute myeloid leukemia patients with KMT2A rearrangement; A nationwide retrospective analysis in Japan.Semantic proximity Read ↗

Outcomes of acute lymphoblastic leukemia with KMT2A (MLL) rearrangement: the MD Anderson experienceSemantic proximity Read ↗

Role of Chromosomal Microarray and RNA Fusion Analysis in Detecting <i>KMT2A</i>-PTD and Stem Cell Transplant Impact on MortalitySemantic proximity Read ↗

The KMT2A recombinome of acute leukemias in 2023Semantic proximity Read ↗

Outcomes and genetic dynamics of acute myeloid leukemia at first relapse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.