Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The KMT2A recombinome of acute leukemias in 2023

5 Apr 2023

Abstract excerpt

Chromosomal rearrangements of the human KMT2A/MLL gene are associated with de novo as well as therapy-induced infant, pediatric, and adult acute leukemias. Here, we present the data obtained from 3401 acute leukemia patients that have been analyzed between 2003 and 2022. Genomic breakpoints within the KMT2A gene and the involved translocation partner genes (TPGs) and KMT2A-partial tandem duplications (PTDs) were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Advanced biosensing and bioanalysis techniques
Share to Protein Degradation and Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37019990
DOI: 10.1038/s41375-023-01877-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The KMT2A recombinome of acute leukemias in 2023PMID 37019990Read ↗

The MLL recombinome of acute leukemias in 2017Semantic proximity Read ↗

KMT2A Rearrangements in Leukemias: Molecular Aspects and Therapeutic PerspectivesSemantic proximity Read ↗

Updates in KMT2A Gene Rearrangement in Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Unveiling the Complexity of KMT2A Rearrangements in Acute Myeloid Leukemias with Optical Genome MappingSemantic proximity Read ↗

Comprehensive immunophenotypic study of acute myeloid leukemia with KMT2A ( MLL ) rearrangement in adults: A single‐institution experienceSemantic proximity Read ↗

Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study.Semantic proximity Read ↗

The MLL recombinome of acute leukemias in 2013Semantic proximity Read ↗

Optimized cytogenetic risk-group stratification of KMT2A -rearranged pediatric acute myeloid leukemiaSemantic proximity Read ↗

Outcomes of acute lymphoblastic leukemia with KMT2A (MLL) rearrangement: the MD Anderson experienceSemantic proximity Read ↗

Epigenetic changes in human model KMT2A leukemias highlight early events during leukemogenesis.Semantic proximity Read ↗

Genomic Characterization of Partial Tandem Duplication Involving the KMT2A Gene in Adult Acute Myeloid LeukemiaSemantic proximity Read ↗

Characteristics and Prognostic Implications in Newly Diagnosed KMT2Ar AML: A Multicenter Study of the ECLA Group.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.