Article
Outcomes and genetic dynamics of acute myeloid leukemia at first relapse.
Haematologica - 1 Nov 2024
Bataller Alex, Kantarjian Hagop, Bazinet Alexandre, Kadia Tapan, Daver Naval, DiNardo Courtney D, Borthakur Gautam, Loghavi Sanam, Patel Keyur, Tang Guilin, Sasaki Koji, Short Nicholas J, Yilmaz Musa, Issa Ghayas C, Alvarado Yesid, Montalban-Bravo Guillermo, Maiti Abhishek, Abbas Hussein A, Takahashi Koichi, Pierce Sherry, Jabbour Elias, Garcia-Manero Guillermo, Ravandi Farhad
Abstract excerpt
Patients with relapsed acute myeloid leukemia (AML) experience dismal outcomes. We performed a comprehensive analysis of patients with relapsed AML to determine the genetic dynamics and factors predicting survival. We analyzed 875 patients with newly diagnosed AML who received intensive treatment or low-intensity treatment. Of these patients, 197 subsequently relapsed. Data were available for 164 of these...
Topics
- Humans
- Leukemia, Myeloid, Acute
- Female
- Male
- Middle Aged
- Adult
- Aged
- Hematopoietic Stem Cell Transplantation
- Mutation