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Secretomes From Non‐Small Cell Lung Cancer Cells Induce Endothelial Plasticity Through a Partial Endothelial‐to‐Mesenchymal Transition

1 Mar 2025

Abstract excerpt

ABSTRACT Aim The tumor microenvironment (TME) of non‐small cell lung cancer (NSCLC) is highly heterogeneous and is involved in tumorigenesis and resistance to therapy. Among the cells of the TME, endothelial cells are associated with the latter processes through endothelial‐to‐mesenchymal transition (EndMT). During EndMT, endothelial cells (ECs) progressively lose their endothelial phenotype in favor of a...

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PMID: 40028673
DOI: 10.1002/cam4.70707

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