Article
Recombinant human endostatin could eliminate the pro-angiogenesis priority of SP cells sorted from non-small cell lung cancer cells.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Aug 2012
Cao Baoshan, Jia Jun, Ma Liwen, Di Lijun, Song Guohong, Yuan Yanhua, Ma Bo, Zhu Yulin, Yu Jing, Wang Xiaoli, Zhou Xinna, Lyerly H Kim, Ren Jun
Abstract excerpt
PURPOSE: To ascertain the biologic significance of lung cancer Side population (SP) cells, which represent putative cancer stem cells (CSC) in the absence of consensus biomarkers for tumor-specific CSC. MATERIALS AND METHODS: We sorted and analyzed the angiogenic features of SP cells, isolated from tumor cell lines based on the exclusion of the DNA dye Hoechst 33342, from the NSCLC cell lines A549 and H460....
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