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The role of endothelial-to-mesenchymal transition in cancer progression

16 Sept 2008

Abstract excerpt

Recent evidence has demonstrated that endothelial-to-mesenchymal transition (EndMT) may have a significant role in a number of diseases. Although EndMT has been previously studied as a critical process in heart development, it is now clear that EndMT can also occur postnatally in various pathologic settings, including cancer and cardiac fibrosis. During EndMT, resident endothelial cells delaminate from an...

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PMID: 18797460
DOI: 10.1038/sj.bjc.6604662

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