Article
Mesenchymal-Epithelial Transition in Fibroblasts of Human Normal Lungs and Interstitial Lung Diseases.
Biomolecules - 4 Mar 2021
Becerril Carina, Montaño Martha, Cisneros José, Mendoza-Milla Criselda, Pardo Annie, Ortiz-Quintero Blanca, Selman Moisés, Ramos Carlos
Abstract excerpt
. In passages above ten and growing very actively, we observed that some human lung fibroblasts cultured under standard conditions were transformed into a lineage of epithelial-like cells (ELC). To systematically evaluate the possible mesenchymal-epithelial transition (MET) occurrence, fibroblasts were obtained from normal lungs and also from lungs affected by idiopathic interstitial diseases. When an unusual...
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