Article
A role for branchpoints in splicing in vivo.
Nature - 1 Jan 2000
Rautmann G, Breathnach R
Abstract excerpt
The nucleotides immediately surrounding intron/exon junctions of genes transcribed by RNA polymerase B can be derived from 'consensus' sequences for donor and acceptor splice sites by only a few base changes. Studies in vivo have underlined the importance of these junction nucleotides for splicin...
Topics
- Base Sequence
- Chromosome Deletion
- DNA, Recombinant
- Globins
- HeLa Cells
- Humans
- Mutation
- Nucleic Acid Precursors
- RNA Splicing
- RNA, Messenger
