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Article

The position of yeast snoRNA-coding regions within host introns is essential for their biosynthesis and for efficient splicing of the host pre-mRNA.

RNA (New York, N.Y.) - 1 Jan 2007

Vincenti Sara, De Chiara Valentina, Bozzoni Irene, Presutti Carlo

Abstract excerpt

Genomic location of sequences encoding small nucleolar RNAs (snoRNAs) is peculiar in all eukaryotes from yeast to mammals: most of them are encoded within the introns of host genes. In Saccharomyces cerevisiae, seven snoRNAs show this location. In this work we demonstrate that the position of snoRNA-coding regions with respect to splicing consensus sequences is critical: yeast strains expressing mutant constructs...

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Identifiers

PMID: 17135484
DOI: 10.1261/rna.251907
PMCID: PMC1705755

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Source receipt: pubmed, retrieved 7 Sept 2026.

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