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Article

Functional insight into East Asian-specific genetic risk loci for Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Feb 2025

Cho Minyoung, Chaudhuri Soumilee, Liu Shiwei, Park Tamina, Huang Yen-Ning, Rosewood Thea, Bice Paula J, Saykin Andrew J, Won Hong-Hee, Nho Kwangsik

Abstract excerpt

INTRODUCTION: The functional study of genetic risk factors for Alzheimer's disease (AD) provides insights into the underlying mechanisms and identification of potential therapeutic targets. Investigating AD-associated genetic loci identified in East Asian populations using single-nucleus RNA-sequencing data may identify novel functional genetic contributors. METHODS: Cell type-specific expression quantitative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39991798
DOI: 10.1002/alz.14553
PMCID: PMC11848548

Genes

CLIC4
KCNJ6
MAPK1IP1L

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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