Article
Genetics of Alzheimer's disease: an East Asian perspective.
Journal of human genetics - 1 Mar 2023
Miyashita Akinori, Kikuchi Masataka, Hara Norikazu, Ikeuchi Takeshi
Abstract excerpt
Alzheimer's disease (AD) is an age-related multifactorial neurodegenerative disorder. Advances in genome technology, including next generation sequencing have uncovered complex genetic effects in AD by analyzing both common and rare functional variants. Multiple lines of evidence suggest that the pathogenesis of AD is influenced by multiple genetic components rather than single genetic factor. Previous genetic...
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