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Article

Whole-genome sequencing study in Koreans identifies novel loci for Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Dec 2024

Kang Moonil, Farrell John J, Zhu Congcong, Park Hyeonseul, Kang Sarang, Seo Eun Hyun, Choi Kyu Yeong, Jun Gyungah R, Won Sungho, Gim Jungsoo, Lee Kun Ho, Farrer Lindsay A

Abstract excerpt

INTRODUCTION: The genetic basis of Alzheimer's disease (AD) in Koreans is poorly understood. METHODS: We performed an AD genome-wide association study using whole-genome sequence data from 3540 Koreans (1583 AD cases, 1957 controls) and single-nucleotide polymorphism array data from 2978 Japanese (1336 AD cases, 1642 controls). Significant findings were evaluated by pathway enrichment and differential gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39428694
DOI: 10.1002/alz.14128
PMCID: PMC11667495

Genes

ROCK2
MICALL1
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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