Article
Distinct genetic risk loci between biopsy-proven renal and non-renal lupus: a 10-year longitudinal cohort.
Rheumatology (Oxford, England) - 1 Jun 2025
Chan Shirley C W, Lei Yao, Yap Desmond Y H, Lee Pamela P W, Lai Wai Ming, Ying Shirley K Y, Leung Alexander M H, Mok Chi Chiu, Lee Ka Lai, Lau Chak Sing, Yang Wanling, Li Philip H
Abstract excerpt
OBJECTIVE: Systemic lupus erythematosus (SLE) is a heterogeneous disease that manifests as different subphenotypes. Distinct subphenotypes, such as lupus nephritis (LN), have been associated with increased genetic risk, but prior studies have been limited by cross-sectional and imprecisely subphenotyped cohorts. This study investigated the genetic basis for LN using a longitudinal cohort of distinctly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.