Article
A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles.
Genes and immunity - 1 Jan 2011
Budarf M L, Goyette P, Boucher G, Lian J, Graham R R, Claudio J O, Hudson T, Gladman D, Clarke A E, Pope J E, Peschken C, Smith C D, Hanly J, Rich E, Boire G, Barr S G, Zummer M, Fortin P R, Wither J, Rioux J D
Abstract excerpt
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Multiple genetic and environmental factors contribute to the pathogenesis of this disease. Recent genome-wide association studies have added substantially to the number of genes associated with SLE. To replicate some of these susceptibility loci, single-nucleotide polymorphisms reported to be associated to SLE were evaluated in a cohort of...
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