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Distinct H3K9me3 and DNA methylation modifications during mouse spermatogenesis

29 Oct 2019

Abstract excerpt

DNA methylation and histone modifications critically regulate the expression of many genes and repeat regions during spermatogenesis. However, the molecular details of these processes in male germ cells remain to be addressed. Here, using isolated murine sperm cells, ultra-low-input native ChIP-Seq (ULI-NChIP-Seq), and whole genome bisulfite sequencing (WGBS), we investigated genome-wide DNA methylation patterns...

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PMID: 31662436
DOI: 10.1074/jbc.ra119.010496

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