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APOE ε4–associated heterogeneity of neuroimaging biomarkers across the Alzheimer's disease continuum

22 Nov 2024

Abstract excerpt

INTRODUCTION: While the role of apolipoprotein E (APOE) ε4 in Alzheimer's disease (AD) susceptibility has been studied extensively, much less is known about the differences in disease presentation in APOE ε4 carriers versus non-carriers. METHODS: To help elucidate these differences, we performed a broad analysis comparing the regional levels of six different neuroimaging biomarkers in the brains of APOE ε4...

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PMID: 39575672
DOI: 10.1002/alz.14392

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