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Article

Correlations between APOE4 allele and regional amyloid and tau burdens in cognitively normal older individuals.

Scientific reports - 22 Aug 2022

Hong Yun Jeong, Kim Chan-Mi, Lee Jae Hong, Sepulcre Jorge

Abstract excerpt

The correlations between apolipoprotein epsilon 4 (APOE4) status and regional amyloid, tau, and cortical thickness in cognitively normal elderly are not fully understood. Our cross-sectional study aimed to compare regional amyloid/tau burden, and cortical thickness according to APOE4 carrier status and assess correlations between APOE4 and Alzheimer's disease (AD)-related biomarker burdens. We analyzed 185...

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Identifiers

PMID: 35995824
DOI: 10.1038/s41598-022-18325-2
PMCID: PMC9395408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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