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Article

Assessing the causal associations of atrial fibrillation with serum uric acid level and gout: insights from a bidirectional mendelian randomization study.

BMC cardiovascular disorders - 13 Nov 2024

Zhu Shoulong, Zhang Mingfang, Cheng Shanshan, Wang Chengjie, Deng Fengfeng

Abstract excerpt

BACKGROUND: Numerous observational studies consistently highlight a strong association between serum uric acid (sUA) levels and atrial fibrillation (AF). However, the causal relationship and the direction of this association remain elusive, despite extensive research efforts. OBJECTIVE: This study aimed to investigate the bidirectional causal relationships between sUA, gout, and the risk of AF using the...

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Identifiers

PMID: 39538126
DOI: 10.1186/s12872-024-04319-7
PMCID: PMC11562312

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