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Article

Disentangling the association between kidney function and atrial fibrillation: a bidirectional Mendelian randomization study.

International journal of cardiology - 15 May 2022

Geurts Sven, van der Burgh Anna C, Bos Maxime M, Ikram M Arfan, Stricker Bruno H C, Deckers Jaap W, Hoorn Ewout J, Chaker Layal, Kavousi Maryam

Abstract excerpt

BACKGROUND: The potential bidirectional causal association between kidney function and atrial fibrillation (AF) remains unclear. METHODS: We conducted a bidirectional two-sample Mendelian randomization (MR) analysis. From multiple genome-wide association studies (GWAS), we retrieved genetic variants associated with kidney function (estimated glomerular filtration rate based on creatinine (eGFRcreat), blood urea...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 35278573
DOI: 10.1016/j.ijcard.2022.03.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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