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Article

Uric Acid Levels and Cardiovascular and Cerebrovascular Diseases: A Mendelian Randomization Study.

Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2025

Hou Xiaowen, Hou Xiaowen, Cen Kaiwen, Zhu Yunfeng, Zhu Zhi, Zhang Zhiyu, Feng Xu

Abstract excerpt

INTRODUCTION: The relationship between uric acid (UA) levels and cardiovascular and cerebrovascular diseases (CCVD) is controversial. A two-sample Mendelian randomization (MR) study was conducted to explore the causal effects of UA levels on CCVD. METHODS: Genetic variants strongly associated with UA levels were selected as instrumental variables from the Genome-Wide Association Study (GWAS) dataset. The GWAS...

Read the complete abstract on PubMed

Topics

Humans
Uric Acid
Mendelian Randomization Analysis
Genome-Wide Association Study
Cerebrovascular Disorders
Risk Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Hyperuricemia

Risk Assessment

Biomarkers

Phenotype

Polymorphism, Single Nucleotide

Atrial Fibrillation

Stroke

Coronary Artery Disease

Cardiovascular Diseases

Source

Identifiers

PMID: 39369690
DOI: 10.1159/000541624

Genes

CAD

Provenance

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