Anterior-posterior constraint on Hedgehog signaling by hhip in teleost fin elaboration.

Abstract excerpt

Pectoral fins, the anterior paired fins in fish, have enhanced maneuvering abilities due to morphological changes. Teleosts have fewer radial bones in their pectoral fins than basal species, resulting in more-elaborate fins. The mechanism behind this radial constraint change in teleosts is unclear. Here, we found that mutations in hhip, which encodes an antagonist of Hedgehog signaling, led to an increase in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Animal Fins
• Share to Gene Expression Regulation, Developmental