Combined mutations of hoxa13a, hoxa13b, and hoxd13a lead to structural shifts in zebrafish soft fin rays providing insight into spiny ray evolution.

Abstract excerpt

The zebrafish hoxa13a, hoxa13b, and hoxd13a genes have been shown to be essential for proper pectoral fin patterning. Combined mutations in these genes cause an elaboration of the pectoral fin endoskeleton, and a size reduction of the rays. In this study, we further examine the impact of partial deletions in these genes on the fin exoskeleton. Using morphological and micro-CT scan analyses, we found that rays of...

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