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Article

Impact of feeding age on cognitive impairment in mice with Disrupted-In-Schizophrenia 1 (Disc1) mutation under a high sucrose diet.

Behavioural brain research - 5 Jan 2025

Park Jonghyuk, Shimbo Hiroko, Tamura Shoko, Tomoda Toshifumi, Hikida Takatoshi, Okado Haruo, Hirai Shinobu

Abstract excerpt

A combination of genetic predisposition and environmental factors contributes to the development of psychiatric disorders such as schizophrenia, bipolar disorder and major depressive disorder. Previous studies using mouse models suggested that prolonged high sucrose intake during puberty can serve as an environmental risk factor for the onset of psychiatric disorders. However, the impact of both the duration and...

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PMID: 39401692
DOI: 10.1016/j.bbr.2024.115291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Impact of feeding age on cognitive impairment in mice with Disrupted-In-Schizophrenia 1 (Disc1) mutation under a high sucrose diet.PMID 39401692Read ↗

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