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Article

Social anhedonia as a Disrupted-in-Schizophrenia 1-dependent phenotype.

Scientific reports - 17 Jun 2022

Seidisarouei Mohammad, Schäble Sandra, van Wingerden Marijn, Trossbach Svenja V, Korth Carsten, Kalenscher Tobias

Abstract excerpt

Deficits in social interaction or social cognition are key phenotypes in a variety of chronic mental diseases, yet, their modeling and molecular dissection are only in their infancy. The Disrupted-in-Schizophrenia 1 (DISC1) signaling pathway is considered to play a role in different psychiatric disorders such as schizophrenia, depression, and biopolar disorders. DISC1 is involved in regulating the dopaminergic...

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Identifiers

PMID: 35715502
DOI: 10.1038/s41598-022-14102-3
PMCID: PMC9205858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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