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Article

Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 22 Oct 2008

Shen Sanbing, Lang Bing, Nakamoto Chizu, Zhang Feng, Pu Jin, Kuan Soh-Leh, Chatzi Christina, He Shuisheng, Mackie Iain, Brandon Nicholas J, Marquis Karen L, Day Mark, Hurko Orest, McCaig Colin D, Riedel Gernot, St Clair David

Abstract excerpt

Disrupted-in-Schizophrenia-1 (DISC1), identified by positional cloning of a balanced translocation (1;11) with the breakpoint in intron 8 of a large Scottish pedigree, is associated with a range of neuropsychiatric disorders including schizophrenia. To model this mutation in mice, we have generat...

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Source

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Identifiers

PMID: 18945897
DOI: 10.1523/JNEUROSCI.3299-08.2008
PMCID: PMC6671369

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18945897-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.PMID 18945897Read ↗

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