Article
Exploring the Relationship of rs2802292 with Diabetes and NAFLD in a Southern Italian Cohort-Nutrihep Study.
International journal of molecular sciences - 1 Sept 2024
Forte Giovanna, Donghia Rossella, Lepore Signorile Martina, Tatoli Rossella, Bonfiglio Caterina, Losito Francesco, De Marco Katia, Manghisi Andrea, Guglielmi Filomena Anna, Disciglio Vittoria, Fasano Candida, Sanese Paola, Cariola Filomena, Buonadonna Antonia Lucia, Grossi Valentina, Giannelli Gianluigi, Simone Cristiano
Abstract excerpt
Background: The minor G-allele of FOXO3 rs2802292 is associated with human longevity. The aim of this study was to test the protective effect of the variant against the association with type 2 Diabetes and NAFLD. Methods: rs2802292 was genotyped in a large population of middle-aged subjects (n = 650) from a small city in Southern Italy. All participants were interviewed to collect information about lifestyle and...
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