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Article

Association Analysis of FOXO3 Longevity Variants With Blood Pressure and Essential Hypertension.

American journal of hypertension - 1 Nov 2016

Morris Brian J, Chen Randi, Donlon Timothy A, Evans Daniel S, Tranah Gregory J, Parimi Neeta, Ehret Georg B, Newton-Cheh Christopher, Seto Todd, Willcox D Craig, Masaki Kamal H, Kamide Kei, Ryuno Hirochika, Oguro Ryosuke, Nakama Chikako, Kabayama Mai, Yamamoto Koichi, Sugimoto Ken, Ikebe Kazunori, Masui Yukie, Arai Yasumichi, Ishizaki Tatsuro, Gondo Yasuyuki, Rakugi Hiromi, Willcox Bradley J

Abstract excerpt

BACKGROUND: The minor alleles of 3 FOXO3 single nucleotide polymorphisms (SNPs)- rs2802292 , rs2253310 , and rs2802288 -are associated with human longevity. The aim of the present study was to test these SNPs for association with blood pressure (BP) and essential hypertension (EHT). METHODS: In a primary study involving Americans of Japanese ancestry drawn from the Family Blood Pressure Program II we genotyped...

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Source

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Identifiers

PMID: 26476085
DOI: 10.1093/ajh/hpv171
PMCID: PMC5055732

Genes

FOXO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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