Article
rs2802292 polymorphism in the FOXO3A gene and exceptional longevity in two ethnically distinct cohorts.
Maturitas - 1 Oct 2016
Fuku Noriyuki, Díaz-Peña Roberto, Arai Yasumichi, Abe Yukiko, Pareja-Galeano Helios, Sanchis-Gomar Fabián, Santos-Lozano Alejandro, Zempo Hirofumi, Naito Hisashi, Murakami Haruka, Miyachi Motohiko, Venturini Letizia, Ricevuti Giovanni, Nobuyoshi Hirose, Emanuele Enzo, Lucia Alejandro
Abstract excerpt
OBJECTIVES: Previous studies have indicated that the rs2802292 polymorphism in the human forkhead box O3A (FOXO3A) gene might be associated with exceptional longevity (EL, i.e., living 100+ years), although the results are conflicting. STUDY DESIGN AND MAIN OUTCOME MEASURES: Using a case-control design, we investigated the distribution of the rs2802292 polymorphism in two ethnically distinct cohorts of...
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