Article
Genome-scale mutational signature analysis in archived fixed tissues.
Mutation research. Reviews in mutation research - 1 Jan 2024
Chavanel Bérénice, Virard François, Cahais Vincent, Renard Claire, Sirand Cécilia, Smits Kim M, Schouten Leo J, Fervers Béatrice, Charbotel Barbara, Abedi-Ardekani Behnoush, Korenjak Michael, Zavadil Jiri
Abstract excerpt
Mutation spectra and mutational signatures in cancerous and non-cancerous tissues can be identified by various established techniques of massively parallel sequencing (or next-generation sequencing) including whole-exome or whole-genome sequencing, and more recently by error-corrected/duplex sequencing. One rather underexplored area has been the genome-scale analysis of mutational signatures as markers of...
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